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Romiplostim

Generic Name: Romiplostim

Brand Names: Nplate

Romiplostim is an injectable thrombopoietin receptor agonist for chronic immune thrombocytopenia.

HematologyBiologic

What It's Used For

Romiplostim is prescribed for:

  • Chronic immune thrombocytopenia (ITP)
  • Patients who have failed other treatments
  • Hematology platelet disorders

Weekly subcutaneous injection that stimulates platelet production.

Side Effects

Common side effects:

  • Headache
  • Fatigue
  • Arthralgia
  • Dizziness
  • Abdominal pain

Serious side effects:

  • Bone marrow fibrosis
  • Thromboembolism
  • Worsening thrombocytopenia after discontinuation

Additional Information

What is Romiplostim?

Romiplostim is a peptibody that binds to and activates the thrombopoietin receptor, stimulating platelet production.

Weekly Injection

Given as weekly subcutaneous injection, with dose adjusted based on platelet response.

Rebound Thrombocytopenia

Platelet counts may drop below baseline after stopping - gradual tapering may be considered.

Learn more at MedlinePlus.

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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