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Anakinra

Generic Name: Anakinra

Brand Names: Kineret

Anakinra is an IL-1 receptor antagonist for rheumatoid arthritis, CAPS, and other autoinflammatory conditions.

RheumatologicBiologic

What It's Used For

Anakinra is prescribed for:

  • Rheumatoid arthritis (moderate to severe)
  • Cryopyrin-associated periodic syndromes (CAPS)
  • Deficiency of IL-1 receptor antagonist (DIRA)
  • Acute gout (off-label)
  • Immunology autoinflammatory conditions

Side Effects

Common side effects:

  • Injection site reactions (very common)
  • Infections
  • Headache
  • Nausea

Serious side effects:

  • Serious infections
  • Neutropenia
  • Hypersensitivity

Additional Information

What is Anakinra?

Anakinra is a recombinant IL-1 receptor antagonist that blocks IL-1 signaling.

Daily Injection

Unlike other biologics, anakinra requires daily subcutaneous injection, which limits its use in RA.

Autoinflammatory Diseases

Highly effective for IL-1-driven autoinflammatory conditions like CAPS, where it can be life-changing.

For more information, see MedlinePlus.

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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