What It's Used For

Certolizumab is prescribed for:

Rheumatoid arthritis
Crohn's disease
Psoriasis and psoriatic arthritis
Ankylosing spondylitis
Immunology and gastrointestinal conditions

Side Effects

Common side effects:

Upper respiratory infections
Rash
Urinary tract infections
Injection site reactions

Serious side effects (boxed warnings):

Serious infections including TB
Malignancy (especially lymphoma)

Additional Information

What is Certolizumab?

Certolizumab is a pegylated anti-TNF antibody fragment (lacks Fc portion).

Unique Structure

The pegylation and lack of Fc region may result in:

Longer half-life
Minimal placental transfer (safest TNF inhibitor in pregnancy)
No complement or antibody-dependent cytotoxicity

Pregnancy Considerations

Preferred TNF inhibitor during pregnancy due to minimal placental transfer.

For details, see MedlinePlus.

Related Health Conditions

This medication is commonly used to treat or manage the following conditions:

Crohn’s disease

Crohn's disease, an inflammatory bowel disease, causes chronic digestive tract inflammation due to genetic, immune, and environmental factors, leading to debilitating symptoms and complications.

Learn More

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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Certolizumab