Benralizumab is prescribed for:
- Severe eosinophilic asthma
- Add-on maintenance treatment
- Reducing oral corticosteroid use
- Respiratory severe disease management
Targets eosinophils through IL-5 receptor binding.
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Benralizumab
Generic Name: Benralizumab
Brand Names: Fasenra
Benralizumab is a biologic that depletes eosinophils for severe eosinophilic asthma.
RespiratoryBiologicMonoclonal Antibody
What It's Used For
Side Effects
Common side effects:
- Headache
- Pharyngitis
- Injection site reactions
- Fever
Serious side effects:
- Hypersensitivity reactions
- Parasitic infection risk
Additional Information
What is Benralizumab?
Benralizumab is a monoclonal antibody that binds to the IL-5 receptor on eosinophils, causing rapid and near-complete eosinophil depletion.
Unique Mechanism
Unlike other anti-IL-5 biologics, benralizumab causes direct eosinophil cell death through antibody-dependent cellular cytotoxicity (ADCC).
Dosing Convenience
After initial doses, administered every 8 weeks (less frequent than some biologics).
For details, see MedlinePlus.
Related Health Conditions
This medication is commonly used to treat or manage the following conditions:
Asthma
Asthma, a chronic lung disease, causes airway inflammation and narrowing, resulting in wheezing, coughing, and shortness of breath, triggered by allergens, irritants, infections, or stress.
Learn More
Attention Deficit Hyperactivity Disorder (ADHD)
ADHD is a neurodevelopmental disorder marked by inattention, hyperactivity, and/or impulsivity, stemming from complex interactions between genetics, brain differences, and environmental factors, not poor parenting.
Learn More
Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.
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