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Dabigatran

Generic Name: Dabigatran Etexilate

Brand Names: Pradaxa

Dabigatran is a direct thrombin inhibitor anticoagulant for stroke prevention in atrial fibrillation and VTE treatment.

CardiovascularAnticoagulant

What It's Used For

Side Effects

Common side effects:

  • Dyspepsia (common)
  • Gastritis-like symptoms
  • Bleeding

Serious side effects:

  • Major bleeding
  • GI bleeding (higher than warfarin)
  • Spinal/epidural hematoma with neuraxial anesthesia

Additional Information

What is Dabigatran?

Dabigatran is a direct thrombin inhibitor that doesn't require INR monitoring.

Reversal Agent

Idarucizumab (Praxbind) is a specific reversal agent for dabigatran in emergencies.

Renal Excretion

80% renally excreted - contraindicated in severe renal impairment and requires dose adjustment in moderate impairment.

For details, see MedlinePlus.

Related Health Conditions

This medication is commonly used to treat or manage the following conditions:

Atrial Fibrillation

Atrial fibrillation, a common arrhythmia characterized by rapid, irregular heartbeats, increases risk of stroke and heart failure, often linked to age, hypertension, and heart disease.

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Osteoarthritis

Osteoarthritis, a common degenerative joint disease, causes pain, stiffness, and reduced motion due to cartilage breakdown from aging, genetics, obesity, injuries, or repetitive stress.

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Stroke

A stroke, caused by interrupted brain blood supply from blockage (ischemic) or bleeding (hemorrhagic), is a medical emergency requiring prompt treatment to minimize brain damage.

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Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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