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Abatacept

Generic Name: Abatacept

Brand Names: Orencia

Abatacept is a T-cell co-stimulation blocker for rheumatoid arthritis, juvenile idiopathic arthritis, and psoriatic arthritis.

RheumatologicBiologic

What It's Used For

Side Effects

Common side effects:

  • Headache
  • Upper respiratory infection
  • Nasopharyngitis
  • Nausea

Serious side effects:

  • Serious infections
  • Malignancy (uncertain)
  • COPD exacerbation in COPD patients

Additional Information

What is Abatacept?

Abatacept is a selective T-cell co-stimulation modulator that interferes with T-cell activation in autoimmune arthritis.

Mechanism

Binds to CD80/CD86 on antigen-presenting cells, preventing the "second signal" needed for T-cell activation.

COPD Caution

More frequent COPD exacerbations and respiratory adverse events in patients with COPD.

Learn more at MedlinePlus.

Related Health Conditions

This medication is commonly used to treat or manage the following conditions:

Chronic Obstructive Pulmonary Disease (COPD)

COPD, a progressive lung disease causing irreversible airflow limitation, encompassing emphysema and chronic bronchitis, is primarily driven by irritant exposure like smoking, leading to shortness of breath and chronic cough.

Learn More

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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