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Dupilumab

Generic Name: Dupilumab

Brand Names: Dupixent

Dupilumab is a biologic that blocks IL-4 and IL-13 for moderate-to-severe atopic dermatitis, asthma, and nasal polyps.

DermatologicBiologicMonoclonal Antibody

What It's Used For

Side Effects

Common side effects:

  • Injection site reactions
  • Conjunctivitis and eye problems
  • Cold sores (oral herpes)
  • Headache

Serious side effects:

  • Hypersensitivity reactions
  • Eye inflammation (keratitis)

Additional Information

What is Dupilumab?

Dupilumab is a monoclonal antibody that blocks IL-4 and IL-13 signaling, key drivers of type 2 inflammation.

Multiple Conditions

Approved for several conditions driven by type 2 inflammation:

Eye Side Effects

Conjunctivitis and keratitis are more common with dupilumab, especially in atopic dermatitis patients.

For details, see MedlinePlus.

Related Health Conditions

This medication is commonly used to treat or manage the following conditions:

Asthma

Asthma, a chronic lung disease, causes airway inflammation and narrowing, resulting in wheezing, coughing, and shortness of breath, triggered by allergens, irritants, infections, or stress.

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Dermatitis

Dermatitis is skin inflammation with varied causes, including irritants, allergens, genetics (eczema), yeast overgrowth, or poor circulation, resulting in itchy rashes and dryness.

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Sinusitis

Sinusitis involves sinus inflammation and blockage due to infections, allergies, or structural issues, causing facial pain, pressure, and congestion, often following colds or triggered by allergens.

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Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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