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Golimumab

Generic Name: Golimumab

Brand Names: Simponi, Simponi Aria

Golimumab is a TNF inhibitor available as monthly subcutaneous or IV infusion for various inflammatory conditions.

RheumatologicGastrointestinalBiologic

What It's Used For

Side Effects

Common side effects:

  • Upper respiratory infection
  • Injection site reactions
  • Nasopharyngitis

Serious side effects (boxed warnings):

  • Serious infections
  • Malignancy
  • Hepatitis B reactivation

Additional Information

What is Golimumab?

Golimumab is a fully human anti-TNF monoclonal antibody.

Dosing Options

  • Simponi: Monthly subcutaneous injection
  • Simponi Aria: IV infusion every 4-8 weeks

Fully Human Antibody

May have lower immunogenicity compared to chimeric antibodies like infliximab.

Learn more at MedlinePlus.

Related Health Conditions

This medication is commonly used to treat or manage the following conditions:

Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory bowel disease causing ulcers and inflammation in the colon and rectum, driven by immune dysfunction, genetics, and environmental factors, leading to symptoms like diarrhea and abdominal pain.

Learn More

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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