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Apremilast

Generic Name: Apremilast

Brand Names: Otezla

Apremilast is an oral PDE4 inhibitor for psoriasis, psoriatic arthritis, and oral ulcers in Behçet's disease.

DermatologicRheumatologic

What It's Used For

Apremilast is prescribed for:

An oral alternative to injectable biologics.

Side Effects

Common side effects:

  • Diarrhea
  • Nausea
  • Upper respiratory infection
  • Headache
  • Weight loss

Serious side effects:

  • Depression and suicidal thoughts
  • Severe diarrhea
  • Weight loss

Additional Information

What is Apremilast?

Apremilast is an oral PDE4 inhibitor that reduces inflammatory cytokines.

Oral Convenience

Unlike biologics, apremilast is an oral medication taken twice daily.

Titration Required

Must be titrated over 5 days to minimize GI side effects.

Learn more at MedlinePlus.

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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