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Dermatitis

Dermatitis is skin inflammation with varied causes, including irritants, allergens, genetics (eczema), yeast overgrowth, or poor circulation, resulting in itchy rashes and dryness.

Dermatologic
Dermatitis is a general term for inflammation of the skin. It can manifest in various forms, often characterized by itchy, dry skin or a rash on swollen, reddened skin. It can be acute (short-term) or chronic (long-term). Causes: Dermatitis can be caused by a variety of factors, and the specific cause often depends on the type of dermatitis:
  • Contact Dermatitis:
    • Irritant Contact Dermatitis: Occurs when the skin comes into contact with irritating substances that damage the skin's protective barrier. Common irritants include strong soaps, detergents, solvents, acids, alkalis, and prolonged exposure to water.
    • Allergic Contact Dermatitis: An allergic reaction occurs when the skin comes into contact with a substance (allergen) to which it has become sensitized. Common allergens include nickel (jewelry), poison ivy/oak/sumac, fragrances, preservatives, certain dyes, and latex.
  • Atopic Dermatitis (Eczema): A chronic inflammatory skin condition with a strong genetic component, often linked to a family history of allergies, asthma, or eczema. It involves a dysfunctional skin barrier and an overactive immune response.
  • Seborrheic Dermatitis: Believed to be caused by an overgrowth of a yeast (Malassezia) that naturally lives on the skin, combined with an inflammatory response. It often affects oily areas of the body.
  • Stasis Dermatitis: Occurs due to poor circulation in the legs, leading to fluid buildup and inflammation. Common in people with varicose veins or other circulatory problems.
  • Nummular Dermatitis (Discoid Eczema): Characterized by coin-shaped patches of irritated skin. The exact cause is unknown but may be linked to dry skin, skin injury, or certain medications.
Symptoms: Symptoms of dermatitis vary depending on the type and severity but commonly include:
  • Itching (pruritus): Often intense and can be worse at night.
  • Rash: Red, swollen, or discolored skin.
  • Dry, flaky, or scaly skin.
  • Blisters: Small, fluid-filled blisters that may ooze and crust over.
  • Thickened skin: In chronic cases, repeated scratching can lead to thickened, leathery skin (lichenification).
  • Cracked skin: Especially with dry skin.
  • Pain or tenderness.
  • Swelling.
Diagnosis: Dermatitis is typically diagnosed by a dermatologist or general practitioner based on a physical examination of the skin and a detailed medical history.
  • Medical history: The doctor will ask about your symptoms, their onset, potential exposures to irritants or allergens, family history of allergies or skin conditions, and any existing medical conditions.
  • Physical examination: The doctor will examine the affected areas of your skin to identify the type and pattern of the rash.
  • Patch testing: For suspected allergic contact dermatitis, small amounts of common allergens are applied to the skin (usually on the back) for 48 hours to see if a reaction occurs.
  • Skin biopsy: In some cases, a small sample of skin may be taken and examined under a microscope to confirm the diagnosis or rule out other conditions.
  • Blood tests: Generally not used to diagnose dermatitis directly, but may be ordered to rule out underlying systemic conditions.
Treatment: Treatment for dermatitis aims to reduce inflammation, relieve itching, and heal the skin. The approach depends on the type and severity of dermatitis.
  • Identify and avoid triggers: This is crucial, especially for contact dermatitis.
  • Topical Medications (applied to the skin):
    • Corticosteroid creams/ointments: Reduce inflammation and itching. Available in various strengths.
    • Calcineurin inhibitors (e.g., tacrolimus, pimecrolimus): Non-steroidal medications that reduce inflammation, often used for atopic dermatitis.
    • Antifungal creams: For seborrheic dermatitis, to control yeast overgrowth.
    • Moisturizers (emollients): Essential for all types of dermatitis, especially dry skin conditions like atopic dermatitis, to restore the skin barrier.
  • Oral Medications (for severe or widespread dermatitis):
    • Antihistamines: Reduce itching, especially sedating ones at night to aid sleep.
    • Oral corticosteroids (e.g., prednisone): For short courses to control severe flare-ups, but not for long-term use due to side effects.
    • Antibiotics: If a bacterial infection is present due to scratching.
    • Immunosuppressants: For severe, chronic cases of atopic dermatitis not responding to other treatments (e.g., cyclosporine, methotrexate).
    • Biologic drugs: Newer injectable medications for severe atopic dermatitis (e.g., dupilumab).
Light therapy (phototherapy): Involves exposing the skin to specific wavelengths of ultraviolet light, often used for chronic or widespread dermatitis.
  • Lifestyle and Home Care:
    • Take lukewarm baths or showers.
    • Use mild, fragrance-free soaps and cleansers.
    • Moisturize frequently, especially after bathing.
    • Avoid scratching; keep nails short.
    • Wear loose-fitting, cotton clothing.
    • Manage stress.
Dermatitis can be a persistent condition, and effective management often involves a combination of treatments and consistent skin care. Working with a dermatologist can help identify the specific type of dermatitis and develop a personalized treatment plan.

Related Medications

Commonly prescribed medications for this condition

DupilumabUpadacitinib