Tocilizumab is prescribed for:
- Rheumatoid arthritis
- Giant cell arteritis
- Polyarticular and systemic juvenile idiopathic arthritis
- Cytokine release syndrome (CAR-T related)
- Immunology conditions
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Tocilizumab
Generic Name: Tocilizumab
Brand Names: Actemra
Tocilizumab is an IL-6 receptor blocker for rheumatoid arthritis, giant cell arteritis, and cytokine release syndrome.
RheumatologicBiologic
What It's Used For
Side Effects
Common side effects:
- Upper respiratory infections
- Headache
- Hypertension
- Injection site reactions
Serious side effects (boxed warning):
- Serious infections
- GI perforation
- Hepatotoxicity
- Lipid abnormalities
Additional Information
What is Tocilizumab?
Tocilizumab blocks the IL-6 receptor, a key inflammatory cytokine.
Unique Features
- Can mask infection signs (no fever, no CRP elevation)
- Significant effect on lipid levels
- GI perforation risk, especially with diverticulitis
Giant Cell Arteritis
Only biologic approved for giant cell arteritis, allowing steroid dose reduction.
For details, see MedlinePlus.
Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.
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