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Secukinumab

Generic Name: Secukinumab

Brand Names: Cosentyx

Secukinumab is an IL-17A inhibitor biologic for psoriasis, psoriatic arthritis, and ankylosing spondylitis.

DermatologicRheumatologicBiologic

What It's Used For

Secukinumab is prescribed for:

  • Moderate-to-severe plaque psoriasis
  • Psoriatic arthritis
  • Ankylosing spondylitis
  • Non-radiographic axial spondyloarthritis
  • Dermatologic autoimmune conditions

Side Effects

Common side effects:

  • Nasopharyngitis
  • Diarrhea
  • Upper respiratory infections
  • Injection site reactions

Serious side effects:

  • Serious infections
  • Inflammatory bowel disease exacerbation
  • Hypersensitivity reactions

Additional Information

What is Secukinumab?

Secukinumab is a monoclonal antibody that blocks IL-17A, a key cytokine in psoriatic disease.

High Efficacy

Achieves PASI 90 (90% skin clearance) in many psoriasis patients.

IBD Caution

May worsen or trigger inflammatory bowel disease. Avoid in patients with active IBD.

Learn more at MedlinePlus.

Related Health Conditions

This medication is commonly used to treat or manage the following conditions:

Osteoarthritis

Osteoarthritis, a common degenerative joint disease, causes pain, stiffness, and reduced motion due to cartilage breakdown from aging, genetics, obesity, injuries, or repetitive stress.

Learn More

Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory bowel disease causing ulcers and inflammation in the colon and rectum, driven by immune dysfunction, genetics, and environmental factors, leading to symptoms like diarrhea and abdominal pain.

Learn More

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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