Lubiprostone is prescribed for:
- Chronic idiopathic constipation
- IBS-C in women
- Opioid-induced constipation
- Gastrointestinal conditions
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Lubiprostone
Generic Name: Lubiprostone
Brand Names: Amitiza
Lubiprostone activates chloride channels in the intestine to treat chronic constipation and IBS-C.
Gastrointestinal
What It's Used For
Side Effects
Common side effects:
- Nausea (most common)
- Diarrhea
- Headache
- Abdominal pain and distension
Nausea can be reduced by taking with food.
Additional Information
What is Lubiprostone?
Lubiprostone is a chloride channel activator that increases intestinal fluid secretion.
Mechanism
Lubiprostone:
- Activates ClC-2 chloride channels
- Increases intestinal fluid
- Softens stool consistency
- Promotes bowel movements
Multiple Indications
Approved for different doses:
- 24 mcg twice daily for chronic constipation
- 8 mcg twice daily for IBS-C in women
For details, see MedlinePlus.
Related Health Conditions
This medication is commonly used to treat or manage the following conditions:
Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.
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