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Misoprostol

Generic Name: Misoprostol

Brand Names: Cytotec

Misoprostol is a prostaglandin analog that protects the stomach lining from NSAID damage.

Gastrointestinal

What It's Used For

Misoprostol is prescribed for:

  • Prevention of NSAID-induced gastric ulcers
  • Gastrointestinal protection during chronic NSAID use
  • Patients on long-term aspirin or NSAID therapy

Side Effects

Common side effects:

  • Diarrhea (common)
  • Abdominal pain
  • Nausea
  • Flatulence
  • Headache

⚠️ CONTRAINDICATED IN PREGNANCY - can cause miscarriage and birth defects.

Additional Information

What is Misoprostol?

Misoprostol is a synthetic prostaglandin E1 analog that replaces protective prostaglandins depleted by NSAIDs.

Mechanism

Misoprostol:

  • Increases mucus and bicarbonate secretion
  • Enhances mucosal blood flow
  • Reduces acid secretion
  • Protects stomach lining

CRITICAL WARNING

⚠️ PREGNANCY CONTRAINDICATION: Misoprostol can cause abortion, premature birth, or birth defects. Women of childbearing potential must use effective contraception.

For details, see MedlinePlus.

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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