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Linaclotide

Generic Name: Linaclotide

Brand Names: Linzess

Linaclotide is used for IBS with constipation and chronic idiopathic constipation by increasing intestinal fluid.

Gastrointestinal

What It's Used For

Side Effects

Common side effects:

  • Diarrhea (most common)
  • Abdominal pain
  • Flatulence
  • Abdominal distension

Serious side effects:

  • Severe diarrhea
  • Dehydration

Additional Information

What is Linaclotide?

Linaclotide is a guanylate cyclase-C agonist that treats IBS-C and chronic constipation.

How It Works

Linaclotide:

  • Activates guanylate cyclase-C receptors
  • Increases intestinal fluid secretion
  • Accelerates intestinal transit
  • Reduces visceral pain

Administration

Take on an empty stomach at least 30 minutes before first meal of the day. Do not give to children under 6.

For more information, see MedlinePlus.

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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