- Simple cysts: Thin-walled sacs of clear fluid with no solid tissue. Their exact cause is not known, but age is the main risk factor and they are not inherited.
- Complex cysts: Cysts with thickened walls, internal partitions, or calcifications. Most are still benign, but a minority can harbor kidney cancer, so radiologists grade them and recommend follow-up imaging or urology referral accordingly.
- Polycystic kidney disease (PKD): An inherited condition in which numerous cysts enlarge both kidneys over time and can gradually impair kidney function. It usually runs strongly in families.
- Acquired cystic disease: People with long-standing kidney failure, especially on dialysis, can develop multiple cysts.
- Dull pain or fullness: An ache in the flank, back, or upper abdomen from a large cyst pressing on nearby structures. This differs from the sudden, severe, cramping pain of kidney stones.
- Infection: Fever and flank pain can occur if a cyst becomes infected.
- Rupture or bleeding: A burst cyst can cause sharp flank pain and blood in the urine.
- High blood pressure and enlarged kidneys: More typical of polycystic kidney disease than of simple cysts.
- Simple, symptom-free cysts: No treatment needed - reassurance is the correct therapy.
- Large, painful cysts: A urologist can drain the cyst and inject a solution that discourages refilling (sclerotherapy), or remove it laparoscopically.
- Infected cysts: Treated with antibiotics, occasionally with drainage.
- Complex cysts and PKD: Managed with scheduled imaging and specialist involvement; protecting kidney function by controlling blood pressure and diabetes matters most in the long run.
- Fever with flank or back pain: This can signal an infected cyst or a kidney infection and should be evaluated the same day.
- Sudden, severe flank pain: A cyst that bleeds or ruptures causes abrupt pain; most episodes settle with rest and fluids, but they should still be checked.
- Visible blood in the urine: Always worth a prompt visit, whether or not you have a known cyst, because several other conditions can produce it.
- Rising blood pressure or reduced urine output: Either finding in someone with multiple cysts calls for a closer look at kidney function.