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Ubrogepant

Generic Name: Ubrogepant

Brand Names: Ubrelvy

Ubrogepant is an oral CGRP receptor antagonist for acute treatment of migraine attacks.

NeurologicMigraine Acute

What It's Used For

Ubrogepant is prescribed for:

Unlike injectables, this is an oral CGRP antagonist for treating acute attacks.

Side Effects

Common side effects:

  • Nausea
  • Somnolence
  • Dry mouth

Generally well tolerated with no cardiovascular contraindications like triptans.

Additional Information

What is Ubrogepant?

Ubrogepant is the first oral CGRP receptor antagonist ("gepant") approved for acute migraine treatment.

Advantages Over Triptans

  • No vasoconstriction (safe in cardiovascular disease)
  • No medication overuse headache concern
  • Can be used with preventive CGRP antibodies

Dosing

50 mg or 100 mg at migraine onset. May repeat once after 2 hours if needed.

Learn more at MedlinePlus.

Related Health Conditions

This medication is commonly used to treat or manage the following conditions:

Migraine

Migraine is a debilitating neurological condition causing recurrent headaches with throbbing pain, nausea, and light/sound sensitivity, likely stemming from complex brain, nerve, and blood vessel interactions.

Learn More

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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