What It's Used For

Lemborexant is prescribed for:

Insomnia with difficulty falling asleep
Insomnia with difficulty staying asleep
Neurologic sleep disorders

Works by blocking wake-promoting orexin signaling.

Side Effects

Common side effects:

Somnolence
Fatigue
Headache
Sleep paralysis
Abnormal dreams

Avoid alcohol and take only when able to sleep 7+ hours.

Additional Information

What is Lemborexant?

Lemborexant is a dual orexin receptor antagonist (DORA) for insomnia.

How It Works

Orexin is a wake-promoting neurotransmitter. By blocking orexin receptors:

Decreases wakefulness
Promotes sleep
Works differently than benzodiazepines or Z-drugs

Advantages

Low abuse potential
Minimal next-day impairment at recommended doses
Helps both falling asleep and staying asleep

For more information, see MedlinePlus.

Related Health Conditions

This medication is commonly used to treat or manage the following conditions:

Lupus Anticoagulant

Lupus anticoagulant is an antibody causing paradoxical prolonged clotting tests yet increasing thrombosis risk, linked to antiphospholipid syndrome and autoimmune diseases, despite not always requiring lupus diagnosis.

Learn More

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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Lemborexant