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Sucralfate

Generic Name: Sucralfate

Brand Names: Carafate

Sucralfate is a mucosal protectant that forms a protective barrier over ulcers to promote healing.

Gastrointestinal

What It's Used For

Sucralfate is prescribed for:

  • Duodenal ulcer treatment
  • Ulcer prevention in critically ill patients
  • Gastrointestinal mucosal protection
  • Stress ulcer prophylaxis

It works locally in the stomach to protect damaged tissue.

Side Effects

Common side effects:

  • Constipation
  • Dry mouth
  • Nausea
  • Stomach discomfort

Serious side effects are rare but include aluminum toxicity in patients with kidney disease.

Additional Information

What is Sucralfate?

Sucralfate is a unique medication that forms a protective paste-like substance that binds to ulcer sites.

How It Works

Sucralfate:

  • Binds to positively charged proteins in ulcer base
  • Forms a physical barrier against acid and pepsin
  • Stimulates prostaglandin and mucus production
  • Does not affect acid production

Administration Tips

Take on an empty stomach, 1 hour before meals. Separate from other medications by 2 hours as it can affect absorption.

Learn more at MedlinePlus.

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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