Menu

Internal MedicineOur MissionOur Team
CardiovascularDermatologicEndocrineENTGastrointestinalGenito-UrinaryHematologyImmunologyMusculoskeletalNeurologicOphthalmologyPsychiatricPulmonaryGLP-1 Medications
All Health ConditionsCardiovascularDermatologicEndocrineENTGastrointestinalGenito-UrinaryHematologyImmunologyMusculoskeletalNeurologicOphthalmologyPsychiatricPulmonary
Medication GuidePatient FormsYour First VisitPatient ResourcesLab VisitsPatient PortalHIPAA PrivacyLocal VitalsFAQ
Supplements
Outbreaks
Contact Us
Back to Medication Guide

Roflumilast

Generic Name: Roflumilast

Brand Names: Daliresp

Roflumilast is an oral PDE4 inhibitor that reduces COPD exacerbations in patients with severe disease.

RespiratoryPDE4 Inhibitor

What It's Used For

Roflumilast is prescribed for:

  • Reducing COPD exacerbations
  • Severe COPD with chronic bronchitis
  • Patients with history of frequent exacerbations
  • Respiratory anti-inflammatory therapy

NOT a bronchodilator - works by reducing inflammation.

Side Effects

Common side effects:

  • Diarrhea
  • Weight loss
  • Nausea
  • Headache
  • Insomnia

Serious side effects:

  • Psychiatric symptoms (depression, suicidal ideation)
  • Weight loss
  • Diarrhea leading to dehydration

Additional Information

What is Roflumilast?

Roflumilast is an oral phosphodiesterase-4 inhibitor that reduces airway inflammation in COPD.

Not a Bronchodilator

Unlike inhalers, roflumilast doesn't provide immediate symptom relief. It reduces inflammation to prevent exacerbations.

Patient Selection

Best for severe COPD patients with chronic bronchitis phenotype and frequent exacerbations despite inhaled therapy.

Learn more at MedlinePlus.

Related Health Conditions

This medication is commonly used to treat or manage the following conditions:

Chronic Obstructive Pulmonary Disease (COPD)

COPD, a progressive lung disease causing irreversible airflow limitation, encompassing emphysema and chronic bronchitis, is primarily driven by irritant exposure like smoking, leading to shortness of breath and chronic cough.

Learn More

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

Loading questions...

Ask Dr. Zimmer

Have questions about Roflumilast? Get expert answers from Dr. Zimmer.

Privacy: Your questions are posted anonymously for your health privacy. Your name and email are only used for admin purposes.

Questions are reviewed before posting. You'll see your question and Dr. Zimmer's answer below once approved.