Fluticasone
Fluticasone is used to treat asthma and allergic rhinitis. It is available as Flovent, Flonase and is commonly prescribed in the respiratory category.
About Fluticasone
Fluticasone is a corticosteroid (inhaled or intranasal glucocorticoid) also sold under brand names including Flovent and Flonase. It is primarily used to is prescribed to treat: • Asthma and allergic rhinitis • Various related conditions in the respiratory category • Associated symptoms and complications It is an important medication that helps manage these conditions effectively. Fluticasone is available in inhalation aerosol hfa (44 mcg, 110 mcg, 220 mcg per actuation — flovent hfa / arnuity), inhalation powder (50 mcg, 100 mcg, 250 mcg per inhalation — flovent diskus), nasal spray (50 mcg/spray — flonase otc; 27.5 mcg/spray fluticasone furoate — veramyst/flonase sensimist), combination inhaler with salmeterol (advair, airduo) or vilanterol (breo ellipta), and topical cream and ointment (0.05%, 0.005%) for dermatologic use form. Healthcare providers commonly prescribe Fluticasone for conditions including Asthma, Attention Deficit Hyperactivity Disorder (ADHD), Lupus Anticoagulant, and Rhinitis.
Fluticasone at a Glance
- Brand names
- Flovent, Flonase
- Drug class
- Corticosteroid (Inhaled or Intranasal Glucocorticoid)
- Pregnancy category
- FDA Category Category C — Animal studies have shown adverse effects at high systemic doses. Inhaled and intranasal fluticasone produce minimal systemic absorption at therapeutic doses and are generally considered acceptable when needed to control asthma or allergic rhinitis during pregnancy. Untreated maternal asthma carries greater fetal risk than continued inhaled corticosteroid therapy.
- Available forms
- Inhalation aerosol HFA (44 mcg, 110 mcg, 220 mcg per actuation — Flovent HFA / Arnuity), Inhalation powder (50 mcg, 100 mcg, 250 mcg per inhalation — Flovent Diskus), Nasal spray (50 mcg/spray — Flonase OTC; 27.5 mcg/spray fluticasone furoate — Veramyst/Flonase Sensimist), Combination inhaler with salmeterol (Advair, AirDuo) or vilanterol (Breo Ellipta), Topical cream and ointment (0.05%, 0.005%) for dermatologic use
- Therapeutic categories
- Respiratory, Corticosteroids, Asthma, Allergies
- Conditions treated
- 5 related conditions on this site
What Fluticasone Is Used For
is prescribed to treat:
• Asthma and allergic rhinitis • Various related conditions in the respiratory category • Associated symptoms and complications
It is an important medication that helps manage these conditions effectively.
Dosage Quick Reference
These are general dosage guidelines for Fluticasone. Your doctor will determine the appropriate dose for your specific situation.
| Condition | Starting Dose | Maintenance Dose |
|---|---|---|
| Persistent asthma — adults (HFA) | 88 mcg twice daily (low dose) | 88–880 mcg twice daily titrated to control |
| Persistent asthma — children 4–11 years | 88 mcg twice daily | 88–176 mcg twice daily |
| Allergic rhinitis — adults (intranasal) | 2 sprays per nostril once daily (200 mcg total) | 1–2 sprays per nostril once daily once controlled |
| Allergic rhinitis — children 4–11 years | 1 spray per nostril once daily | 1–2 sprays per nostril once daily |
| Maintenance COPD (Breo Ellipta — fluticasone furoate/vilanterol) | 100/25 mcg one inhalation once daily | 100/25 mcg once daily |
Side Effects
Common side effects may include:
• Nausea or stomach upset • Headache • Dizziness or lightheadedness • Fatigue or tiredness • Mild rash or itching
Serious side effects (seek immediate medical attention):
• Severe allergic reactions (rash, hives, swelling, difficulty breathing) • Unusual bleeding or bruising • Severe stomach pain • Signs of liver problems (yellowing of skin/eyes, dark urine) • Chest pain or irregular heartbeat • Severe dizziness or fainting • Signs of serious adverse effects
See also: Drug Interactions ↓
Drug Interactions
Inhaled and intranasal fluticasone produce limited systemic exposure at recommended doses, but interactions can become clinically important when systemic absorption increases.
- Strong CYP3A4 inhibitors (e.g., ritonavir, cobicistat, ketoconazole, itraconazole, clarithromycin): Can dramatically raise systemic fluticasone levels, leading to Cushing syndrome, adrenal suppression, and growth retardation in children. Avoid or use the lowest effective dose with close monitoring; consider switching to beclomethasone or budesonide.
- Long-acting beta agonists (salmeterol, vilanterol, formoterol): Frequently combined with fluticasone for asthma and COPD. The combination is more effective than either alone, but LABAs should not be used as monotherapy in asthma due to mortality risk.
- Other systemic or inhaled corticosteroids: Additive HPA-axis suppression. If a patient needs an oral steroid burst, monitor for cumulative cortisol suppression and consider stress-dose coverage in major illness or surgery.
- Live vaccines (in immunosuppressed or high-dose users): Usually safe with low-to-moderate inhaled doses but use caution with chronic high-dose inhaled or systemic exposure.
- Beta blockers (especially non-selective such as propranolol): Can blunt the bronchodilator response to rescue inhalers used alongside fluticasone. Cardioselective beta blockers are preferred when needed.
See also: Questions to Ask Your Doctor ↓
Key Considerations
Known drug interactions
Fluticasone has documented interactions with other medications, supplements, and certain foods. Review the Drug Interactions section below and tell your healthcare provider about every medication you take, including over-the-counter products. Jump to section →
Multiple forms available
Fluticasone comes in more than one form (Inhalation aerosol HFA (44 mcg, 110 mcg, 220 mcg per actuation — Flovent HFA / Arnuity), Inhalation powder (50 mcg, 100 mcg, 250 mcg per inhalation — Flovent Diskus), Nasal spray (50 mcg/spray — Flonase OTC; 27.5 mcg/spray fluticasone furoate — Veramyst/Flonase Sensimist), Combination inhaler with salmeterol (Advair, AirDuo) or vilanterol (Breo Ellipta), Topical cream and ointment (0.05%, 0.005%) for dermatologic use). The right form for you depends on your condition, ease of use, and your provider's recommendation.
Additional Information
What is ?
Fluticasone (generic name: Fluticasone) is a medication primarily used to treat asthma and allergic rhinitis. It is marketed under the brand name(s) Flovent, Flonase and belongs to the Respiratory category of medications.
How Does Fluticasone Work?
Fluticasone works through several mechanisms to provide therapeutic benefits:
- Acts on specific receptors or pathways in the body
- Modulates biological processes related to the treated condition
- Provides symptom relief and improves quality of life
- Helps manage the underlying condition effectively
- Works best when combined with appropriate lifestyle modifications
The medication is designed to target the specific pathways involved in asthma and allergic rhinitis, making it an effective treatment option.
Common Uses
Primary Indications
Fluticasone is commonly prescribed for:
- Asthma and allergic rhinitis: The main indication for this medication
- Related Conditions: Associated symptoms and complications
- Prevention: May help prevent progression of certain conditions
- Symptom Management: Reduces discomfort and improves daily function
Additional Uses
In some cases, Fluticasone may also be prescribed for:
- Off-label uses as determined by your healthcare provider
- Combination therapy with other medications
- Long-term management of chronic conditions
- Short-term treatment of acute symptoms
Dosage and Administration
Fluticasone dosing varies based on the specific condition being treated and individual patient factors.
Typical Dosing:
- Starting dose is typically determined by your healthcare provider
- May be adjusted based on response and tolerability
- Can be taken with or without food (follow specific instructions)
- Usually taken once or twice daily
Administration Tips:
- Take at the same time(s) each day for best results
- Swallow tablets/capsules whole unless instructed otherwise
- Don't skip doses
- Complete full course of treatment as prescribed
- Follow your doctor's specific instructions carefully
Important Safety Information
Who Should Not Take Fluticasone?
Do not take Fluticasone if you:
- Are allergic to Fluticasone or any ingredients
- Have certain medical conditions (discuss with your doctor)
- Are taking medications that interact with Fluticasone
- Have severe liver or kidney disease (without dose adjustment)
Drug Interactions
Inform your doctor about all medications you take, including:
- Prescription medications
- Over-the-counter drugs
- Vitamins and supplements
- Herbal products
Some medications may interact with Fluticasone, affecting its efficacy or increasing side effect risk.
Pregnancy and Breastfeeding
Pregnancy:
- Discuss risks and benefits with your doctor if pregnant or planning pregnancy
- May require special monitoring or dose adjustments
- Some medications should be avoided during pregnancy
Breastfeeding:
- Consult your doctor about safety while breastfeeding
- May pass into breast milk
- Benefits and risks should be carefully considered
Monitoring and Follow-Up
While taking Fluticasone, your doctor may monitor:
- Effectiveness of treatment (symptom improvement)
- Side effects or adverse reactions
- Laboratory values if applicable
- Blood pressure, heart rate, or other vital signs as appropriate
- Overall response to therapy
Regular follow-up appointments are important to ensure the medication is working properly and to make any necessary adjustments.
Managing Side Effects
Most side effects are mild and improve with time. Here are strategies for common side effects:
Gastrointestinal Upset
- Take with food if allowed
- Stay well hydrated
- Eat smaller, more frequent meals
- Report persistent nausea or vomiting
Dizziness
- Rise slowly from sitting or lying positions
- Avoid sudden movements
- Stay hydrated
- Avoid alcohol
- Report severe or persistent dizziness
Fatigue
- Get adequate rest
- Maintain regular sleep schedule
- Exercise as tolerated
- Report excessive tiredness that interferes with daily activities
Lifestyle Considerations
To maximize the benefits of Fluticasone:
- Follow a healthy, balanced diet
- Exercise regularly as recommended by your doctor
- Maintain a healthy weight
- Avoid alcohol or limit consumption
- Don't smoke
- Manage stress through relaxation techniques
- Get adequate sleep
- Stay well hydrated
- Keep all follow-up appointments
- Take medication consistently as prescribed
When to Contact Your Doctor
Seek immediate medical attention if you experience:
- Signs of severe allergic reaction (difficulty breathing, severe rash, swelling)
- Chest pain or rapid heartbeat
- Severe dizziness or fainting
- Unusual bleeding or bruising
- Signs of liver problems (yellowing of skin/eyes, dark urine, severe fatigue)
- Severe stomach pain
- Any symptoms that concern you
Contact your doctor for non-emergency issues:
- Mild to moderate side effects that persist
- Questions about your medication
- Concerns about effectiveness
- New medications prescribed by another doctor
- Scheduled surgery or dental procedures
- Planning pregnancy
Storage
Store Fluticasone at room temperature (68-77°F or 20-25°C) away from light, heat, and moisture. Keep in original container. Keep out of reach of children and pets. Do not use past expiration date.
Important Reminders
- Take exactly as prescribed by your doctor
- Don't stop suddenly without medical advice
- Keep all follow-up appointments
- Report any unusual symptoms
- Don't share medication with others
- Store safely away from children
- Check expiration dates
- Ask your pharmacist if you have questions
Clinical Benefits
When used appropriately, Fluticasone provides several benefits:
- Effective management of asthma and allergic rhinitis
- Improvement in quality of life
- Reduction in symptoms
- Prevention of complications
- Generally well-tolerated when used as directed
- Backed by clinical research and extensive use
Disclaimer: This information is for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your physician or other qualified healthcare provider with any questions about a medical condition or medication.
Frequently Asked Questions
Questions to Ask Your Doctor About Fluticasone
Consider discussing these topics at your next appointment:
- Am I using the right inhaler technique — could you watch me demonstrate it?
- Do I still need fluticasone if I feel fine, or can we step down the dose?
- How will we know if my asthma or rhinitis is well controlled, and what symptoms should prompt me to call?
- Are any of my other medications increasing the systemic effects of fluticasone?
- Should I be on a combination inhaler (with a long-acting bronchodilator), and what are the trade-offs?
Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.