- Stimulants: Caffeine, nicotine, alcohol, energy drinks, and some cold medicines can provoke extra beats.
- Stress and poor sleep: Anxiety, fatigue, and adrenaline all make the heart more irritable.
- Electrolyte imbalances: Low potassium or magnesium levels commonly trigger PVCs.
- Thyroid problems: An overactive thyroid speeds and sensitizes the heart; see hyperthyroidism.
- Underlying heart disease: Coronary artery disease, prior heart attack, and cardiomyopathy can produce frequent PVCs and make them more significant.
- Trigger reduction: Cutting back caffeine, alcohol, and nicotine, improving sleep, and managing stress often noticeably reduce symptoms. Keeping a log of palpitations alongside caffeine, alcohol, and sleep often reveals a personal pattern worth changing.
- Correcting reversible causes: Replacing low potassium or magnesium and treating thyroid disease can eliminate PVCs entirely.
- Medications: When symptoms are bothersome, beta-blockers such as metoprolol or calcium channel blockers such as verapamil can suppress the extra beats.
- Catheter ablation: For a very high PVC burden or PVCs arising from a single identifiable spot, ablation can eliminate the source — important because tens of thousands of PVCs per day can gradually weaken the heart muscle, a reversible condition called PVC-induced cardiomyopathy.