- Coronary artery disease: Narrowed heart arteries and prior heart attacks are the leading cause; see coronary artery disease.
- Long-standing high blood pressure: Years of pumping against elevated pressure thicken and stiffen the heart muscle.
- Valve problems: Leaky or narrowed heart valves force the heart to work harder; see valvular heart disease.
- Diseases of the heart muscle: Conditions described under cardiomyopathy, including damage from viral infections or excess alcohol.
- Rhythm problems: A persistently rapid rhythm such as atrial fibrillation can weaken the heart over time.
- Other contributors: Diabetes, obesity, sleep apnea, and certain chemotherapy medications also raise the risk. Finding and treating these contributors is part of a complete heart-failure plan.
- Shortness of breath: With activity, when lying flat, or waking you from sleep at night.
- Swelling (edema): In the feet, ankles, legs, or abdomen as fluid accumulates.
- Rapid weight gain: Several pounds over a few days usually reflects retained fluid, not fat.
- Fatigue and weakness: Everyday tasks feel harder because muscles receive less oxygen-rich blood.
- Persistent cough or wheezing: Sometimes with white or pink-tinged mucus from fluid in the lungs.
- Diuretics: Water pills such as furosemide relieve congestion by helping the kidneys remove excess fluid.
- ACE inhibitors: Medications such as lisinopril relax blood vessels and reduce the heart's workload.
- Beta-blockers: Medications such as carvedilol and metoprolol slow the heart and help the muscle recover strength.
- SGLT2 inhibitors: Medications such as dapagliflozin and empagliflozin improve outcomes in both major forms of heart failure.
- Aldosterone antagonists: Medications such as spironolactone provide additional protection in selected patients.
- Daily habits: Limiting sodium, weighing yourself every morning, staying active, and avoiding excess alcohol are essential parts of treatment, and many patients benefit from a written action plan describing what to do when weight or symptoms change.