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Vilazodone

Generic Name: Vilazodone

Brand Names: Viibryd

Vilazodone is an antidepressant combining SSRI activity with serotonin receptor agonism for treating major depressive disorder.

PsychiatricAntidepressantSSRI

What It's Used For

Side Effects

Common side effects:

  • Diarrhea
  • Nausea
  • Dizziness
  • Insomnia
  • Dry mouth

Serious side effects:

  • Suicidal thoughts (especially in young adults)
  • Serotonin syndrome
  • Bleeding risk
  • Mania activation

Additional Information

What is Vilazodone?

Vilazodone is a novel antidepressant for major depressive disorder that works through a dual mechanism.

Unique Mechanism

Vilazodone:

  • Inhibits serotonin reuptake (like SSRIs)
  • Partially activates 5-HT1A receptors
  • May have faster onset of action
  • May cause less sexual dysfunction than typical SSRIs

Administration

Must be taken with food to improve absorption. Start at 10 mg daily, gradually increasing to 40 mg.

For more information, see MedlinePlus.

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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