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Cariprazine

Generic Name: Cariprazine

Brand Names: Vraylar

Cariprazine is an atypical antipsychotic used for schizophrenia, bipolar disorder, and as an add-on for depression.

PsychiatricAntipsychotic

What It's Used For

Side Effects

Common side effects:

  • Extrapyramidal symptoms (movement disorders)
  • Akathisia (restlessness)
  • Nausea
  • Insomnia
  • Weight gain

Serious side effects:

  • Tardive dyskinesia
  • Metabolic changes
  • Neuroleptic malignant syndrome

Additional Information

What is Cariprazine?

Cariprazine is an atypical antipsychotic with unique receptor binding properties for schizophrenia and bipolar disorder.

Unique Properties

Cariprazine has:

  • High affinity for D3 receptors
  • Partial D2 receptor agonism
  • May improve negative symptoms of schizophrenia
  • Effective for bipolar depression

Long Half-Life

The active metabolites have very long half-lives (1-3 weeks), so effects may persist after discontinuation.

For more information, see MedlinePlus.

Related Health Conditions

This medication is commonly used to treat or manage the following conditions:

Bipolar Disorder

Bipolar disorder, characterized by alternating manic/hypomanic and depressive episodes impacting mood, energy, and daily function, is likely caused by a mix of genetics, brain factors, and triggers.

Learn More

Attention Deficit Hyperactivity Disorder (ADHD)

ADHD is a neurodevelopmental disorder marked by inattention, hyperactivity, and/or impulsivity, stemming from complex interactions between genetics, brain differences, and environmental factors, not poor parenting.

Learn More

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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