Menu

Back to Medication Guide

Ribociclib

Generic Name: Ribociclib

Brand Names: Kisqali

Ribociclib is a CDK4/6 inhibitor for advanced HR+/HER2- breast cancer with proven survival benefit.

OncologyCDK4/6 Inhibitor

What It's Used For

Ribociclib is prescribed for:

  • HR-positive, HER2-negative advanced breast cancer
  • Pre/perimenopausal and postmenopausal women
  • With endocrine therapy
  • Oncology targeted treatment

Demonstrated overall survival benefit in clinical trials.

Side Effects

Common side effects:

  • Neutropenia
  • Nausea
  • Fatigue
  • Diarrhea
  • Alopecia

Serious side effects:

  • QT prolongation (requires ECG monitoring)
  • Hepatotoxicity
  • Severe neutropenia

Additional Information

What is Ribociclib?

Ribociclib is a CDK4/6 inhibitor with demonstrated overall survival improvement.

ECG Monitoring

Requires ECG monitoring due to QT prolongation risk - at baseline, day 14 of cycle 1, and as indicated.

Survival Benefit

One of few targeted therapies to show overall survival benefit in advanced breast cancer.

For more information, see MedlinePlus.

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

Loading questions...

Ask Dr. Zimmer

Have questions about Ribociclib? Get expert answers from Dr. Zimmer.

Privacy: Your questions are posted anonymously for your health privacy. Your name and email are only used for admin purposes.

Questions are reviewed before posting. You'll see your question and Dr. Zimmer's answer below once approved.