Hydroxyurea is prescribed for:
- Sickle cell disease (reduces crises)
- Polycythemia vera
- Essential thrombocythemia
- Chronic myelogenous leukemia
- Hematology blood disorders
In sickle cell, increases fetal hemoglobin production.
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Hydroxyurea
Generic Name: Hydroxyurea
Brand Names: Hydrea, Droxia, Siklos
Hydroxyurea is used for sickle cell disease, certain cancers, and myeloproliferative disorders.
HematologyOncology
What It's Used For
Side Effects
Common side effects:
- Bone marrow suppression
- Nausea
- Skin changes
- Hair loss
- Mouth sores
Serious side effects:
- Severe myelosuppression
- Cutaneous vasculitis
- Secondary malignancy (long-term)
Additional Information
What is Hydroxyurea?
Hydroxyurea is an antimetabolite that inhibits DNA synthesis and increases fetal hemoglobin in sickle cell disease.
Sickle Cell Benefits
Reduces:
- Pain crises by 50%
- Hospitalizations
- Blood transfusion needs
- Acute chest syndrome
Monitoring
Regular blood count monitoring required due to myelosuppression.
For details, see MedlinePlus.
Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.
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