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Abemaciclib

Generic Name: Abemaciclib

Brand Names: Verzenio

Abemaciclib is a CDK4/6 inhibitor for advanced breast cancer that can be used as monotherapy.

OncologyCDK4/6 Inhibitor

What It's Used For

Abemaciclib is prescribed for:

  • HR-positive, HER2-negative advanced breast cancer
  • With endocrine therapy
  • Monotherapy after progression on prior therapies
  • High-risk early breast cancer (adjuvant)
  • Oncology targeted therapy

Side Effects

Common side effects:

  • Diarrhea (very common)
  • Neutropenia
  • Fatigue
  • Nausea
  • Abdominal pain

Serious side effects:

  • Severe diarrhea
  • Interstitial lung disease
  • Venous thromboembolism

Additional Information

What is Abemaciclib?

Abemaciclib is a CDK4/6 inhibitor with continuous dosing and diarrhea as its dose-limiting toxicity.

Continuous Dosing

Unlike palbociclib and ribociclib, given continuously without a week off.

Monotherapy Option

Only CDK4/6 inhibitor approved as monotherapy after prior treatment failure.

Learn more at MedlinePlus.

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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