Imatinib is prescribed for:
- Chronic myeloid leukemia (CML)
- Gastrointestinal stromal tumors (GIST)
- Philadelphia chromosome-positive ALL
- Oncology targeted therapy
The first successful targeted cancer therapy.
Back to Medication Guide
Imatinib
Generic Name: Imatinib Mesylate
Brand Names: Gleevec
Imatinib is a tyrosine kinase inhibitor that revolutionized treatment of chronic myeloid leukemia and GIST.
OncologyTyrosine Kinase Inhibitor
What It's Used For
Side Effects
Common side effects:
- Fluid retention/edema
- Nausea
- Muscle cramps
- Rash
- Diarrhea
Serious side effects:
- Severe fluid retention
- Hepatotoxicity
- Myelosuppression
- Cardiac toxicity
Additional Information
What is Imatinib?
Imatinib revolutionized cancer treatment as the first successful tyrosine kinase inhibitor, turning CML from a fatal disease into a manageable chronic condition.
Historic Success
Changed CML from median survival of 3-5 years to near-normal life expectancy for most patients.
Chronic Treatment
Usually continued indefinitely, though treatment-free remission may be possible for some patients.
For details, see MedlinePlus.
Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.
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