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Paliperidone

Generic Name: Paliperidone

Brand Names: Invega

Paliperidone is an atypical antipsychotic available in oral and long-acting injectable forms for schizophrenia and schizoaffective disorder.

PsychiatricAntipsychotic

What It's Used For

Paliperidone is prescribed for:

Available as daily oral tablets or monthly/3-monthly injections (Invega Sustenna/Trinza).

Side Effects

Common side effects:

  • Tachycardia
  • Headache
  • Somnolence
  • Akathisia
  • Weight gain

Serious side effects:

  • QT prolongation
  • Tardive dyskinesia
  • Hyperprolactinemia
  • Neuroleptic malignant syndrome

Additional Information

What is Paliperidone?

Paliperidone is the active metabolite of risperidone, used to treat schizophrenia and schizoaffective disorder.

Long-Acting Injectables

Paliperidone is available as:

  • Invega Sustenna (monthly injection)
  • Invega Trinza (every 3 months)
  • Invega Hafyera (every 6 months)

These long-acting formulations improve medication adherence.

Monitoring

Regular monitoring for metabolic effects, movement disorders, and prolactin levels is recommended.

Learn more at MedlinePlus.

Related Health Conditions

This medication is commonly used to treat or manage the following conditions:

Osteoarthritis

Osteoarthritis, a common degenerative joint disease, causes pain, stiffness, and reduced motion due to cartilage breakdown from aging, genetics, obesity, injuries, or repetitive stress.

Learn More

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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