- Alzheimer's disease: The most common cause, marked by abnormal protein deposits that gradually damage brain cells. Learn more about Alzheimer's disease.
- Vascular dementia: Damage from an earlier stroke or from chronic narrowing of small brain vessels, often related to high blood pressure and diabetes.
- Lewy body dementia: Abnormal protein deposits that cause fluctuating attention, visual hallucinations, and movement changes; a related process causes dementia in some people with Parkinson's disease.
- Frontotemporal dementia: A less common form, often beginning earlier in life, that first affects personality, behavior, or language.
- Mixed dementia: Particularly in advanced age, Alzheimer's changes and blood-vessel damage frequently occur together in the same brain, which is why symptoms do not always fit one pattern neatly.
- Reversible contributors: Thyroid disease, vitamin B12 deficiency, medication side effects, and untreated sleep apnea can worsen — or occasionally mimic — dementia and should always be checked.
- Memory loss that disrupts life: Repeating questions, missing appointments, relying heavily on notes and reminders.
- Trouble with familiar tasks: Difficulty managing finances, medications, cooking, or driving routes.
- Language problems: Struggling to find words or follow conversations.
- Disorientation: Getting lost in familiar places or confusing dates and seasons.
- Trouble with visual and spatial skills: Misjudging distances, difficulty reading, or becoming turned around on a familiar driving route.
- Misplacing items: Putting objects in unusual places and being unable to retrace steps to find them.
- Changes in judgment, mood, or personality: Poor financial decisions, withdrawal from activities, apathy, suspicion, or irritability.
- Cholinesterase inhibitors: Medications such as donepezil modestly improve memory symptoms in Alzheimer's and some related dementias.
- Memantine: Often added in moderate to severe disease to help thinking and daily function.
- Vascular risk control: Treating blood pressure, cholesterol, and diabetes helps protect remaining brain function.
- Structure and safety: Consistent routines, home-safety measures, driving assessment, and advance planning for finances and care preferences.
- Managing behavior and sleep: Agitation, night-time wandering, and suspicion respond best to predictable routines, daytime activity, good lighting, and treating pain or infection before any medication is considered.
- Caregiver support: Education, respite, and community resources are a core part of treatment.