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Tick-Borne Illness in Pinellas County — Including Alpha-Gal Syndrome
Dr. Michael Zimmer

Dr. Michael A. Zimmer

Tick-Borne Illness in Pinellas County — Including Alpha-Gal Syndrome

Medically reviewed by Michael A. Zimmer, MD, MACPBoard-Certified Internal Medicine, Medical Director
Post Summary

Ticks are active year-round in Florida, and they carry more than Lyme disease. From Rocky Mountain spotted fever to the growing problem of alpha-gal syndrome (an acquired red-meat allergy), here is what to watch for after yard work, hikes, or a weekend at the park.

Ticks Are a Year-Round Florida Problem

Most patients think of ticks as a summer problem in the Northeast. In Pinellas County, they are a 12-month reality. Our mild winters mean populations never really drop, and our mix of coastal scrub, pine flatwoods, oak hammocks, and well-irrigated yards gives several species a comfortable home. You do not have to hike the Croom Tract to pick one up — they turn up after an afternoon in the garden, a walk at Sawgrass Lake, or a weekend visiting family with a dog.

The diseases ticks carry here are different from Lyme country, and one of the newer concerns — alpha-gal syndrome — is not an infection at all. It is an acquired food allergy. Here is what every St. Petersburg adult should know.

The Ticks You Are Actually Encountering

Three species account for most of what we see in Pinellas County:

  • Lone Star tick. Aggressive, fast-moving, and the primary culprit behind alpha-gal syndrome. Females have a distinctive white dot on the back.
  • American dog tick and brown dog tick. Common on dogs and their owners. The brown dog tick is the main vector for Rocky Mountain spotted fever in Florida.
  • Black-legged (deer) tick. Present but much less common than in the Northeast, which is one reason Lyme disease is rare here.

The CDC tick overview and the Florida Department of Health's tick-borne disease page track local activity and case trends.

The Illnesses to Know

In our practice, the tick-borne conditions we watch for are:

  • Rocky Mountain spotted fever (RMSF). Fever, severe headache, and a rash that often starts on wrists and ankles, typically 2-14 days after a bite. Untreated RMSF can be fatal; prompt doxycycline is the treatment of choice, even in children.
  • Ehrlichiosis and anaplasmosis. Flu-like illness with fever, muscle aches, and sometimes low platelets or abnormal liver tests. Also treated with doxycycline.
  • Lyme disease. Uncommon in Florida but not zero. Classic bull's-eye rash and later joint or neurologic symptoms.
  • Alpha-gal syndrome (discussed below).
  • Tularemia and southern tick-associated rash illness (STARI) — much less common, but on the list.

Because several of these present similarly early on, we often start empiric doxycycline in patients with fever and a known tick bite, rather than waiting for blood test confirmation. Amoxicillin plays a role in early Lyme disease in children and pregnant patients who cannot take doxycycline.

Alpha-Gal Syndrome: The Red-Meat Allergy

Alpha-gal is a sugar molecule found in the tissues of most mammals — beef, pork, lamb, venison, rabbit, and many dairy products — but not in humans, fish, or poultry. When a Lone Star tick bites, it can transfer alpha-gal into the skin and trigger the immune system to produce IgE antibodies against it. The next time you eat a burger, your body reacts as though it has been stung.

What makes alpha-gal unusual is the delay. Classic food allergies strike within minutes. Alpha-gal reactions typically appear 3 to 6 hours after eating mammalian meat — often at 2 a.m. after a steak dinner. Presentations include:

  • Hives and intense itching
  • Abdominal cramping, nausea, vomiting, and diarrhea
  • Swelling of the lips, tongue, or throat
  • Frank anaphylaxis with low blood pressure and difficulty breathing

Because the reaction is so delayed, many patients go months or years before the pattern is recognized. We test with a simple blood IgE for alpha-gal when the story fits. The CDC's alpha-gal page has a helpful patient primer.

Treatment is avoidance of mammalian meat and often dairy and gelatin — plus an epinephrine auto-injector for severe reactors. Some patients see their alpha-gal IgE levels drop over years if they can avoid further tick bites.

How to Remove a Tick Properly

The single most important tool is a pair of fine-tipped tweezers. Skip the matches, petroleum jelly, nail polish, and twisting.

  1. Grasp the tick as close to the skin as possible.
  2. Pull straight up with steady, even pressure. Do not twist or jerk.
  3. If the mouthparts stay behind, try once more with the tweezers; if they will not come out, leave them alone and let the skin heal.
  4. Clean the bite with soap and water or rubbing alcohol.
  5. Save the tick in a sealed plastic bag or piece of tape in case we need to identify it later. Note the date.

Flag-level symptoms — fever, spreading rash, severe headache, joint pain — in the two weeks after a bite need a same-day phone call. Do not wait it out.

Prevention That Actually Works

The yard work, gardening, and paddleboarding you love do not have to stop. Layering prevention is what keeps ticks off you.

  • DEET 20-30% on exposed skin for adults and most children over 2 months.
  • Picaridin 20% is an excellent DEET alternative with less odor.
  • Permethrin-treated clothing and shoes. This is the single most effective step for yard workers and hikers; one treatment lasts through several washes.
  • Tuck pants into socks in brush and tall grass. Light-colored clothing makes ticks easier to spot.
  • Full-body tick check within two hours of coming inside — behind the knees, groin, waistband, armpits, scalp, and behind the ears.
  • Shower soon after outdoor exposure to wash off unattached ticks.
  • Treat pets with a veterinarian-recommended preventive year-round; dogs are a common way ticks get into the house.

Our Florida gardener health and safety checklist folds tick prevention into a broader yard-work plan, including sun, heat, and bug spray timing.

After the Bite, and Living With Alpha-Gal

Two questions come up in almost every tick visit: whether the bite itself needs treatment, and, for patients with alpha-gal syndrome, how far the avoidance list really extends.

The bite itself

A small red bump that itches for a few days is a normal reaction to tick saliva and needs nothing more than soap, water, and an antihistamine such as cetirizine if the itch is bothersome. Redness that spreads outward, becomes warm and painful, or arrives with fever may be cellulitis, a skin infection that needs an antibiotic. We do not prescribe a preventive dose of doxycycline after every bite; that practice comes from Lyme-endemic states and does not apply to the ticks we see here. What we do want is the date of the bite and the tick in a bag, because that turns a vague fever two weeks later into a fast diagnosis. The CDC's Rocky Mountain spotted fever page describes the illness that most needs early treatment in Florida.

What alpha-gal avoidance actually covers

Beef, pork, lamb, and venison are the obvious items. The less obvious ones are gelatin in candies and capsules, some dairy for the more sensitive patients, and a handful of medical products derived from mammal tissue, including certain heparin preparations, some vaccines, and some surgical materials. Tell every clinician, dentist, and pharmacist you see, and carry your epinephrine if you have been prescribed it. Fish, poultry, and eggs are safe. Sensitivity varies enormously between patients, and our immunology team can help decide how strict your list needs to be. The CDC's alpha-gal syndrome overview keeps a current list of products to watch.

Keeping the yard from restocking the problem

Every new Lone Star tick bite can raise alpha-gal antibody levels again, so prevention matters more once you have the syndrome, not less. Permethrin on shoes and pants, repellent on skin, and a mowed buffer between lawn and brush are the measures with evidence behind them, as the CDC's tick bite prevention page outlines. The same habits protect against the fire ants and wasps covered in our Florida sting allergy guide, and our gardener safety checklist folds them into a yard-work routine.

When to Call Us

Call the same day for fever, spreading rash, severe headache, or unexplained joint pain after a known or suspected bite. Call sooner if you have ever had an unexplained middle-of-the-night allergic reaction after red meat — that alone is worth an alpha-gal test.

Schedule a visit with Zimmer Medical Group in St. Petersburg, FL to review your tick exposure, testing options, and an individualized prevention plan for your home and yard. You can book a visit here.

Frequently Asked Questions

Usually not. Preventive doxycycline after a bite is a Lyme-country practice tied to the black-legged tick, which is uncommon here. What we treat is illness: fever, headache, rash, or muscle aches within about two weeks of a bite, and in that case we start doxycycline promptly rather than waiting for test results. Keep the tick and note the date so the picture is clear if symptoms appear.
With a blood test for IgE antibodies to alpha-gal, ordered when the story fits: hives, stomach cramps, or a more severe reaction three to six hours after eating beef, pork, or lamb, often in the middle of the night. A positive test plus a matching history makes the diagnosis. A positive result without symptoms does not by itself require avoiding red meat, so the history matters as much as the number.
Sometimes. Antibody levels fall in many patients over a period of years if they avoid further tick bites, and some are eventually able to tolerate mammalian meat again under supervision. That is not guaranteed, and each new Lone Star tick bite can push levels back up, which is why tick prevention becomes the most important part of managing the condition.
Not for everyone. Most patients tolerate dairy; a minority react to it and need to avoid it. Gelatin, found in some candies, marshmallows, and medication capsules, causes reactions in a subset of patients. We usually start by removing mammalian meat and organ meats, then adjust the list based on whether symptoms persist. Tell your pharmacist and any surgeon so mammal-derived products can be avoided.