Menu

Internal MedicineOur MissionOur Team
CardiovascularDermatologicEndocrineENTGastrointestinalGenito-UrinaryHematologyImmunologyMusculoskeletalNeurologicOphthalmologyPsychiatricPulmonaryGLP-1 Medications
All Health ConditionsCardiovascularDermatologicEndocrineENTGastrointestinalGenito-UrinaryHematologyImmunologyMusculoskeletalNeurologicOphthalmologyPsychiatricPulmonary
Medication GuidePatient FormsYour First VisitPatient ResourcesLab VisitsPatient PortalHIPAA PrivacyLocal VitalsFAQ
Supplements
Outbreaks
Contact Us
Back to Medication Guide

Ranolazine

Generic Name: Ranolazine

Brand Names: Ranexa

Ranolazine is a unique antianginal medication that works differently from nitrates, used for chronic angina.

CardiovascularAntianginal

What It's Used For

Ranolazine is prescribed for:

It can be used alone or with other antianginal medications.

Side Effects

Common side effects:

  • Dizziness
  • Headache
  • Constipation
  • Nausea

Serious side effects:

  • QT prolongation
  • Syncope
  • Renal failure worsening

Additional Information

What is Ranolazine?

Ranolazine is a novel antianginal medication that works through a different mechanism than traditional nitrates or beta-blockers.

Unique Mechanism

Ranolazine works by:

  • Inhibiting late sodium current in cardiac cells
  • Reducing calcium overload
  • Improving diastolic function
  • NOT affecting heart rate or blood pressure significantly

Advantages

Unlike other antianginals, ranolazine:

  • Doesn't cause tolerance
  • Minimal hemodynamic effects
  • Can be added to existing therapy

Learn more at MedlinePlus.

Related Health Conditions

This medication is commonly used to treat or manage the following conditions:

Attention Deficit Hyperactivity Disorder (ADHD)

ADHD is a neurodevelopmental disorder marked by inattention, hyperactivity, and/or impulsivity, stemming from complex interactions between genetics, brain differences, and environmental factors, not poor parenting.

Learn More

Osteoarthritis

Osteoarthritis, a common degenerative joint disease, causes pain, stiffness, and reduced motion due to cartilage breakdown from aging, genetics, obesity, injuries, or repetitive stress.

Learn More

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

Loading questions...

Ask Dr. Zimmer

Have questions about Ranolazine? Get expert answers from Dr. Zimmer.

Privacy: Your questions are posted anonymously for your health privacy. Your name and email are only used for admin purposes.

Questions are reviewed before posting. You'll see your question and Dr. Zimmer's answer below once approved.