Generic Name: Amlodipine
Brand Names: Norvasc
Amlodipine is a calcium channel blocker used to treat high blood pressure and chest pain (angina). It works by relaxing blood vessels so blood can flow more easily.
is prescribed to treat:
• High blood pressure (hypertension) • Chronic stable angina (chest pain) • Vasospastic angina (Prinzmetal's angina) • Coronary artery disease • Often combined with other blood pressure medications
It helps prevent strokes, heart attacks, and kidney problems.
Common side effects may include:
• Swelling of ankles or feet (peripheral edema) • Dizziness or lightheadedness • Flushing (feeling of warmth) • Headache • Fatigue • Palpitations • Nausea
Serious side effects (seek immediate medical attention):
• Severe dizziness or fainting • Very fast or irregular heartbeat • Severe swelling of hands, feet, or ankles • Severe stomach pain • Yellowing of skin or eyes • Chest pain (new or worsening) • Shortness of breath • Severe allergic reactions
Amlodipine, commonly known by its brand name Norvasc, is one of the most frequently prescribed medications for high blood pressure in the United States. It belongs to a class of drugs called calcium channel blockers (CCBs), specifically the dihydropyridine subclass.
Amlodipine works by blocking calcium channels in blood vessel walls and heart muscle:
Unlike some other calcium channel blockers (like diltiazem or verapamil), amlodipine primarily affects blood vessels rather than the heart directly, so it doesn't significantly slow heart rate.
Chronic Stable Angina:
Vasospastic Angina (Prinzmetal's Angina):
Coronary Artery Disease:
Amlodipine is typically taken once daily:
For Hypertension:
For Angina:
Administration Tips:
Use caution if you have:
Inform your doctor about all medications, especially:
Major Interactions:
Other Medications:
Pregnancy:
Breastfeeding:
While taking amlodipine, monitor:
Blood Pressure:
Heart Rate:
Edema (Swelling):
Liver Function:
This is the most common side effect, occurring in 10-30% of patients:
Characteristics:
Management Strategies:
Elderly Patients:
Liver Disease:
Kidney Disease:
Heart Failure:
To maximize amlodipine's benefits:
Effective Blood Pressure Control:
Well-Tolerated:
Cardiovascular Protection:
Metabolically Neutral:
Seek immediate medical attention if you experience:
Contact your doctor for non-emergency issues:
Amlodipine is frequently combined with:
ACE Inhibitors or ARBs:
Statins:
Diuretics:
Beta-Blockers:
Major studies demonstrate that amlodipine:
Store amlodipine at room temperature (68-77°F/20-25°C) away from light and moisture. Keep in original container. Protect from excessive heat. Keep out of reach of children.
Amlodipine is available as an affordable generic medication. It's on most $4 generic lists and covered by virtually all insurance plans. Generic amlodipine is bioequivalent to brand-name Norvasc and costs significantly less.
If switching from another calcium channel blocker or blood pressure medication:
Disclaimer: This information is for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your physician or other qualified healthcare provider with any questions about a medical condition or medication.
This medication is commonly used to treat or manage the following conditions:
Atrial fibrillation, a common arrhythmia characterized by rapid, irregular heartbeats, increases risk of stroke and heart failure, often linked to age, hypertension, and heart disease.
ADHD is a neurodevelopmental disorder marked by inattention, hyperactivity, and/or impulsivity, stemming from complex interactions between genetics, brain differences, and environmental factors, not poor parenting.
Coronary Artery Disease (CAD) results from plaque buildup in coronary arteries (atherosclerosis), restricting blood flow and potentially causing angina, heart attack, or heart failure, influenced by factors like high blood pressure and cholesterol.
Heart failure stemming from coronary artery disease arises from narrowed arteries restricting blood flow, weakening or stiffening the heart muscle and reducing its pumping efficiency.
Osteoarthritis, a common degenerative joint disease, causes pain, stiffness, and reduced motion due to cartilage breakdown from aging, genetics, obesity, injuries, or repetitive stress.
Portal hypertension, an elevated pressure in the portal vein due to blockage often from cirrhosis or other pre-hepatic causes, can lead to serious complications like bleeding and ascites.
Secondary pulmonary hypertension, unlike its primary form, arises from underlying conditions such as heart/lung disease, blood clots, or connective tissue disorders, increasing lung artery pressure.
A stroke, caused by interrupted brain blood supply from blockage (ischemic) or bleeding (hemorrhagic), is a medical emergency requiring prompt treatment to minimize brain damage.
Vertigo, a spinning sensation distinct from dizziness, often stems from inner ear or brain issues like BPPV or Meniere's, sometimes triggered by head trauma or medication.
Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.
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