Menu

Back to Medication Guide

Raloxifene

Generic Name: Raloxifene Hydrochloride

Brand Names: Evista

Raloxifene is a selective estrogen receptor modulator (SERM) for osteoporosis that also reduces breast cancer risk.

EndocrineBone Health

What It's Used For

Raloxifene is prescribed for:

  • Postmenopausal osteoporosis treatment and prevention
  • Invasive breast cancer risk reduction
  • Endocrine bone and cancer prevention

Acts like estrogen on bone but blocks estrogen in breast tissue.

Side Effects

Common side effects:

  • Hot flashes
  • Leg cramps
  • Peripheral edema
  • Flu syndrome

Serious side effects (boxed warning):

  • ⚠️ Venous thromboembolism (DVT, PE)
  • Stroke in women with coronary heart disease

Additional Information

What is Raloxifene?

Raloxifene is a selective estrogen receptor modulator (SERM) that has estrogen-like effects on bone but anti-estrogen effects on breast and uterus.

Dual Benefit

Unique among osteoporosis drugs:

  • Treats osteoporosis
  • Reduces risk of invasive breast cancer by ~65%

Blood Clot Risk

Increases risk of DVT and PE. Avoid in women with history of blood clots or those immobilized.

Learn more at MedlinePlus.

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

Loading questions...

Ask Dr. Zimmer

Have questions about Raloxifene? Get expert answers from Dr. Zimmer.

Privacy: Your questions are posted anonymously for your health privacy. Your name and email are only used for admin purposes.

Questions are reviewed before posting. You'll see your question and Dr. Zimmer's answer below once approved.