Bazedoxifene-conjugated estrogens is prescribed for:
- Moderate-to-severe vasomotor symptoms of menopause
- Osteoporosis prevention in postmenopausal women
- Endocrine menopausal management
Alternative to estrogen plus progestin for women with a uterus.
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Bazedoxifene-Conjugated Estrogens
Generic Name: Conjugated Estrogens/Bazedoxifene
Brand Names: Duavee
This combination pairs estrogen with a SERM to treat menopause symptoms and prevent osteoporosis without progestin.
EndocrineBone HealthHormone Therapy
What It's Used For
Side Effects
Common side effects:
- Muscle spasms
- Nausea
- Diarrhea
- Abdominal pain
- Neck pain
Serious side effects (boxed warnings):
- ⚠️ Endometrial cancer (estrogen alone)
- ⚠️ Cardiovascular disorders
- ⚠️ Breast cancer
- ⚠️ Dementia
Additional Information
What is Bazedoxifene-Conjugated Estrogens?
This combination pairs conjugated estrogens with bazedoxifene, a SERM that protects the uterus from estrogen stimulation.
No Progestin Needed
The bazedoxifene component protects against endometrial hyperplasia, eliminating the need for progestin in women with a uterus.
Tissue Selective Estrogen Complex (TSEC)
First and only TSEC approved, offering a novel approach to menopausal hormone therapy.
For details, see MedlinePlus.
Related Health Conditions
This medication is commonly used to treat or manage the following conditions:
Osteoporosis
Osteoporosis weakens bones due to age, hormonal changes, poor diet, medications, certain medical conditions, and lifestyle factors, increasing fracture risk even from minor incidents.
Learn More
Osteoarthritis
Osteoarthritis, a common degenerative joint disease, causes pain, stiffness, and reduced motion due to cartilage breakdown from aging, genetics, obesity, injuries, or repetitive stress.
Learn More
Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.
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