Menu

Back to Medication Guide

Isosorbide Mononitrate

Generic Name: Isosorbide Mononitrate

Brand Names: Imdur, Monoket

Isosorbide mononitrate is a nitrate medication used to prevent angina (chest pain) by dilating blood vessels.

CardiovascularNitrate

What It's Used For

Side Effects

Common side effects:

  • Headache (very common initially)
  • Dizziness
  • Lightheadedness
  • Flushing
  • Nausea

Serious side effects:

  • Severe hypotension
  • Fainting
  • Rapid heartbeat
  • Methemoglobinemia (rare)

Additional Information

What is Isosorbide Mononitrate?

Isosorbide mononitrate is a long-acting nitrate medication used to prevent angina attacks in patients with coronary artery disease.

How It Works

This medication:

  • Dilates blood vessels (venous and arterial)
  • Reduces the heart's workload
  • Decreases oxygen demand
  • Improves blood flow to the heart

Important Notes

  • A nitrate-free interval (usually at night) is needed to prevent tolerance
  • Do NOT use with PDE5 inhibitors (sildenafil, tadalafil)
  • Not for acute angina treatment

Learn more at MedlinePlus.

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

Loading questions...

Ask Dr. Zimmer

Have questions about Isosorbide Mononitrate? Get expert answers from Dr. Zimmer.

Privacy: Your questions are posted anonymously for your health privacy. Your name and email are only used for admin purposes.

Questions are reviewed before posting. You'll see your question and Dr. Zimmer's answer below once approved.