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Entecavir

Generic Name: Entecavir

Brand Names: Baraclude

Entecavir is a first-line antiviral for chronic hepatitis B with high potency and low resistance.

AntiviralHepatitis

What It's Used For

Entecavir is prescribed for:

  • Chronic hepatitis B infection
  • Treatment-naive and lamivudine-refractory patients
  • Compensated and decompensated liver disease
  • Gastrointestinal liver conditions

First-line treatment option with high barrier to resistance.

Side Effects

Common side effects:

  • Headache
  • Fatigue
  • Dizziness
  • Nausea

Serious side effects:

  • Lactic acidosis
  • Severe hepatitis flare upon discontinuation
  • Hepatomegaly with steatosis

Additional Information

What is Entecavir?

Entecavir is a nucleoside analog that inhibits hepatitis B virus replication.

Long-Term Treatment

Hepatitis B treatment is typically lifelong - stopping can cause severe disease flare.

Resistance

Very low resistance rate in treatment-naive patients, but higher in lamivudine-experienced patients.

For more information, see MedlinePlus.

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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