Menu

Back to Medication Guide

Darunavir

Generic Name: Darunavir

Brand Names: Prezista

Darunavir is a protease inhibitor used with ritonavir or cobicistat for HIV treatment.

AntiviralHIV

What It's Used For

Darunavir is prescribed for:

  • HIV-1 infection treatment
  • Treatment-experienced patients with resistance
  • Immunology infectious disease

One of the most potent protease inhibitors with high barrier to resistance.

Side Effects

Common side effects:

  • Diarrhea
  • Nausea
  • Headache
  • Rash

Serious side effects:

  • Severe skin reactions (Stevens-Johnson syndrome)
  • Hepatotoxicity
  • Diabetes/hyperglycemia
  • Redistribution of body fat

Additional Information

What is Darunavir?

Darunavir is a second-generation HIV protease inhibitor that must be boosted with ritonavir or cobicistat.

Sulfa Allergy

Contains a sulfonamide moiety - use with caution in patients with sulfa allergy.

High Resistance Barrier

Effective even in patients with resistance to other protease inhibitors.

Learn more at MedlinePlus.

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

Loading questions...

Ask Dr. Zimmer

Have questions about Darunavir? Get expert answers from Dr. Zimmer.

Privacy: Your questions are posted anonymously for your health privacy. Your name and email are only used for admin purposes.

Questions are reviewed before posting. You'll see your question and Dr. Zimmer's answer below once approved.