- Limited sun exposure: Working indoors, covering the skin, and consistent sunscreen use reduce production.
- Older age: Aging skin produces vitamin D less efficiently, and the kidneys activate it less well.
- Darker skin: Melanin reduces the skin's vitamin D production from the same amount of sun.
- Malabsorption: Digestive conditions such as celiac disease and Crohn's disease, and prior gastric bypass surgery, impair absorption of this fat-soluble vitamin.
- Obesity: Vitamin D is sequestered in fat tissue, lowering blood levels.
- Limited dietary intake: Very few foods naturally contain vitamin D, so diets low in fish, eggs, and fortified dairy supply little.
- Kidney or liver disease and certain medications: Both organs help activate vitamin D, and some seizure and steroid medicines speed its breakdown.
- Bone pain and tenderness: Severe deficiency softens bone — rickets in children and osteomalacia in adults.
- Muscle weakness and aches: Particularly in the hips and thighs, sometimes contributing to falls in older adults.
- Fatigue: Nonspecific, but frequently reported.
- Bone thinning over time: Chronic deficiency contributes to osteopenia and osteoporosis and raises fracture risk.
- Supplementation: Over-the-counter vitamin D3 (cholecalciferol) taken daily is the mainstay; significant deficiency is often treated first with several weeks of higher prescription-strength dosing, then a maintenance dose.
- Dietary sources: Fatty fish, egg yolks, and fortified milk and cereals contribute modest amounts.
- Sensible sun exposure: Brief, regular time outdoors helps, balanced against skin cancer risk — an important consideration in Florida.
- Treating the underlying cause: Malabsorption and kidney disease require tailored management, and levels are rechecked after about three months to confirm correction.
- Osteomalacia: Softening of adult bone that causes deep, aching bone pain, tenderness over the ribs and hips, and in advanced cases small stress fractures.
- Secondary hyperparathyroidism: When calcium absorption falls, the parathyroid glands work harder and draw calcium out of the skeleton, a pattern that overlaps with hyperparathyroidism and accelerates bone loss.
- Falls and fractures: Weakness in the hip and thigh muscles combined with thinner bone raises fracture risk, a particular concern for older adults living independently.
- Rickets in children: Severe deficiency during growth causes bowed legs, delayed milestones, and skeletal deformity — uncommon today, but still seen.