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Dutasteride

Generic Name: Dutasteride

Brand Names: Avodart

Dutasteride is a 5-alpha reductase inhibitor for BPH that shrinks the prostate over time.

Urology5-Alpha Reductase Inhibitor

What It's Used For

Dutasteride is prescribed for:

Inhibits both types of 5-alpha reductase (vs finasteride inhibits only type 2).

Side Effects

Common side effects:

  • Impotence
  • Decreased libido
  • Ejaculation disorders
  • Breast enlargement/tenderness

Serious side effects:

  • High-grade prostate cancer risk
  • Depression
  • PSA reduction (masks prostate cancer detection)

Additional Information

What is Dutasteride?

Dutasteride blocks conversion of testosterone to DHT, reducing prostate size in BPH.

Slow Onset

Takes 3-6 months to see full benefit - for immediate symptom relief, often combined with alpha-blocker.

PSA Reduction

Reduces PSA by about 50% - must double measured PSA value for screening purposes.

Learn more at MedlinePlus.

Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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