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Darifenacin

Generic Name: Darifenacin

Brand Names: Enablex

Darifenacin is a selective M3 muscarinic antagonist for overactive bladder with less cognitive effects.

UrologyAnticholinergic

What It's Used For

Darifenacin is prescribed for:

Most selective for M3 receptors in the bladder.

Side Effects

Common side effects:

  • Constipation
  • Dry mouth
  • Dyspepsia
  • Headache
  • UTI

Less cognitive effects than non-selective anticholinergics.

Additional Information

What is Darifenacin?

Darifenacin is highly selective for M3 muscarinic receptors, which are responsible for bladder contraction.

Cognitive Advantage

M3 selectivity means less effect on M1 receptors in the brain - potentially better for elderly patients.

Constipation

Constipation may be more common than with other anticholinergics.

For more information, see MedlinePlus.

Related Health Conditions

This medication is commonly used to treat or manage the following conditions:

Attention Deficit Hyperactivity Disorder (ADHD)

ADHD is a neurodevelopmental disorder marked by inattention, hyperactivity, and/or impulsivity, stemming from complex interactions between genetics, brain differences, and environmental factors, not poor parenting.

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Osteoarthritis

Osteoarthritis, a common degenerative joint disease, causes pain, stiffness, and reduced motion due to cartilage breakdown from aging, genetics, obesity, injuries, or repetitive stress.

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Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.

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