Generic Name: Adalimumab
Brand Names: Humira
Adalimumab is used to treat rheumatoid arthritis, psoriasis, Crohn's disease, and other inflammatory conditions. It is available as Humira and is commonly prescribed in the immunology category.
Drug Class
Anti-TNF-alpha (Tumor Necrosis Factor) Monoclonal Antibody
Pregnancy
Category B — Animal reproduction studies have not demonstrated fetal harm. Adalimumab crosses the placenta, particularly in the third trimester, and may persist in infant serum for months after birth. Live vaccines should be avoided in exposed infants for at least 6 months. Decisions about continuation during pregnancy should weigh disease control against neonatal immunosuppression risk.
Available Forms
Subcutaneous injection prefilled syringe (10 mg/0.1 mL, 20 mg/0.2 mL, 40 mg/0.4 mL, 80 mg/0.8 mL), Subcutaneous injection prefilled pen (40 mg/0.4 mL, 80 mg/0.8 mL), Subcutaneous injection single-dose vial (40 mg/0.8 mL — institutional use)
Adalimumab is prescribed to treat:
• Rheumatoid arthritis, psoriasis, crohn's disease, and other inflammatory conditions • Various related conditions in the immunology category • Associated symptoms and complications
It is an important medication that helps manage these conditions effectively.
These are general dosage guidelines. Your doctor will determine the appropriate dose for your specific situation.
| Condition | Starting Dose | Maintenance Dose |
|---|---|---|
| Rheumatoid arthritis / Psoriatic arthritis / Ankylosing spondylitis | 40 mg SC every other week | 40 mg SC every other week; may increase to weekly if not on methotrexate |
| Plaque psoriasis (adult) | 80 mg SC at week 0 | 40 mg SC every other week starting week 1 |
| Crohn disease / Ulcerative colitis (adult induction) | 160 mg SC day 1, then 80 mg at week 2 | 40 mg SC every other week starting week 4 |
| Hidradenitis suppurativa | 160 mg SC day 1, then 80 mg at week 2 | 40 mg SC weekly starting week 4 |
| Juvenile idiopathic arthritis (>= 2 years, weight-based) | 10–40 mg SC every other week per weight band | Continue every other week per weight band |
Common side effects may include:
• Nausea or stomach upset • Headache • Dizziness or lightheadedness • Fatigue or tiredness • Mild rash or itching
Serious side effects (seek immediate medical attention):
• Severe allergic reactions (rash, hives, swelling, difficulty breathing) • Unusual bleeding or bruising • Severe stomach pain • Signs of liver problems (yellowing of skin/eyes, dark urine) • Chest pain or irregular heartbeat • Severe dizziness or fainting • Signs of serious adverse effects
Adalimumab is a biologic that suppresses TNF-alpha-mediated immune signaling, so most clinically important interactions are immunological rather than pharmacokinetic.
Adalimumab (generic name: Adalimumab) is a medication primarily used to treat rheumatoid arthritis, psoriasis, Crohn's disease, and other inflammatory conditions. It is marketed under the brand name(s) Humira and belongs to the Immunology category of medications.
Adalimumab works through several mechanisms to provide therapeutic benefits:
The medication is designed to target the specific pathways involved in rheumatoid arthritis, psoriasis, Crohn's disease, and other inflammatory conditions, making it an effective treatment option.
Adalimumab is commonly prescribed for:
In some cases, Adalimumab may also be prescribed for:
Adalimumab dosing varies based on the specific condition being treated and individual patient factors.
Typical Dosing:
Administration Tips:
Do not take Adalimumab if you:
Inform your doctor about all medications you take, including:
Some medications may interact with Adalimumab, affecting its efficacy or increasing side effect risk.
Pregnancy:
Breastfeeding:
While taking Adalimumab, your doctor may monitor:
Regular follow-up appointments are important to ensure the medication is working properly and to make any necessary adjustments.
Most side effects are mild and improve with time. Here are strategies for common side effects:
To maximize the benefits of Adalimumab:
Seek immediate medical attention if you experience:
Contact your doctor for non-emergency issues:
Store Adalimumab at room temperature (68-77°F or 20-25°C) away from light, heat, and moisture. Keep in original container. Keep out of reach of children and pets. Do not use past expiration date.
When used appropriately, Adalimumab provides several benefits:
Disclaimer: This information is for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your physician or other qualified healthcare provider with any questions about a medical condition or medication.
Consider discussing these topics at your next appointment:
This medication is commonly used to treat or manage the following conditions:
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Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.
Other medications in the same category
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