Methadone is prescribed for:
- Opioid use disorder (in OTP clinics)
- Severe chronic pain
- Psychiatric addiction medicine
Long half-life allows once-daily dosing.
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Methadone
Generic Name: Methadone Hydrochloride
Brand Names: Dolophine, Methadose
Methadone is a long-acting opioid used for opioid use disorder treatment and severe chronic pain.
Addiction MedicinePainOpioid
What It's Used For
Side Effects
Common side effects:
- Constipation
- Sweating
- Sedation
- Nausea
Serious side effects (boxed warnings):
- ⚠️ Respiratory depression
- ⚠️ QT prolongation
- ⚠️ Accidental exposure/overdose
- ⚠️ Opioid addiction liability
Additional Information
What is Methadone?
Methadone is a long-acting full opioid agonist used for addiction treatment and chronic pain.
OTP Requirement
For opioid use disorder, can only be dispensed through federally certified Opioid Treatment Programs (OTPs).
QT Prolongation
Requires ECG monitoring, especially at higher doses or with other QT-prolonging medications.
For more information, see MedlinePlus.
Related Health Conditions
This medication is commonly used to treat or manage the following conditions:
Medical Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting, stopping, or changing any medication. Your doctor can provide personalized recommendations based on your specific health condition and medical history.
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