- Bacterial infection: The most common cause of chronic gastritis is infection with Helicobacter pylori (H. pylori). This bacterium can live in the stomach lining and cause inflammation and ulcers.
- Regular use of nonsteroidal anti-inflammatory drugs (NSAIDs): Medications like ibuprofen, naproxen, and aspirin can irritate the stomach lining and cause both acute and chronic gastritis.
- Excessive alcohol consumption: Alcohol can irritate and erode the stomach lining.
- Stress: Severe physical stress from major surgery, burns, or severe infections can cause acute gastritis.
- Autoimmune gastritis: The body's immune system mistakenly attacks cells in the stomach lining.
- Bile reflux: A backflow of bile from the small intestine into the stomach.
- Other infections: Viral, fungal, or parasitic infections, though less common.
- Cocaine use: Can damage the stomach lining.
- Radiation therapy: To the stomach area.
- Crohn's disease: An inflammatory bowel disease that can affect the stomach.
- Aging: The stomach lining tends to thin with age, making it more susceptible to damage.
- Gnawing or burning ache or pain (indigestion) in your upper abdomen: This pain may worsen or improve with eating.
- Nausea.
- Vomiting.
- Feeling of fullness in your upper abdomen after eating.
- Loss of appetite.
- Bloating.
- Black, tarry stools (melena) or vomiting blood: These are signs of bleeding in the stomach and require immediate medical attention.
- Medical history and physical exam: Your doctor will ask about your symptoms, lifestyle, medication use, and any relevant medical conditions.
- Tests for H. pylori:
- Breath test: You drink a clear liquid, and then breathe into a bag.
- Stool test: Checks for H. pylori antigens in your stool.
- Blood test: Checks for H. pylori antibodies (less common for active infection).
- Endoscopy with biopsy: A thin, flexible tube with a camera (endoscope) is inserted down your throat into your stomach to visualize the stomach lining. A small tissue sample (biopsy) may be taken for microscopic examination to check for inflammation, H. pylori, or other abnormalities.
- Upper gastrointestinal (GI) series (barium swallow): X-rays are taken after you swallow a barium solution, which coats the stomach lining, making it visible on X-rays. This is less common for gastritis diagnosis but can help identify ulcers or other structural issues.
- Stool test: To check for blood in the stool, which can indicate bleeding in the stomach.
- Treating H. pylori infection:
- A combination of antibiotics and a proton pump inhibitor (PPI) is typically prescribed for 10-14 days to eradicate the bacteria.
- Avoiding irritants:
- Discontinue or reduce the use of NSAIDs.
- Reduce or eliminate alcohol consumption.
- Avoid spicy, acidic, or fatty foods that can aggravate symptoms.
- Medications to reduce stomach acid:
- Antacids: Over-the-counter medications that neutralize stomach acid for quick relief.
- H2 blockers: Reduce acid production (e.g., famotidine, cimetidine).
- Proton pump inhibitors (PPIs): Block acid production more powerfully than H2 blockers (e.g., omeprazole, lansoprazole, esomeprazole).
- Lifestyle changes:
- Eat smaller, more frequent meals.
- Manage stress through relaxation techniques.
- Avoid smoking.
- Identify and avoid personal food triggers.
- Vitamin B12 supplements: For autoimmune gastritis, as it can impair B12 absorption.